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Creating a world without cancer.

Research

Resources: BIOLOGICAL EVALUATION

Biological Evaluation

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Overview

In cancer biology, mouse models continue to play significant roles in studies of tumor invasion, metastasis and malignant transformation, as well as in studies examining responses to therapy. Key advancements have emerged in the development of animal models for cancer biology, including the advent of orthotopic models for metastasis, transgenic animals that have developmental pathways to tumorigenesis, and state-of-the-art immunocompromised strains. Transplanted human xenografts remain a primary tool for molecular discovery and evaluation. Despite their flaws and shortcomings, xenograft mouse models have played a significant role in cancer drug development in the past three decades, and mouse models will continue to be a foundation in the war against cancer.

At the Purdue University Center for Cancer Research (PCCR) where a vast pipeline of potential new agents for diagnosing and treating cancer are emerging, researchers need a productive and established facility for in vivo testing which can navigate the arena of murine cancer models. The mission of the Biological Evaluation Shared Resource (BE-SR) is to provide expert guidance to investigators in grant preparation, model selection and experimental design, and to perform toxicity testing and proof-of-concept efficacy studies to advance their projects using in vivo testing.

Equipment

Services & Pricing

*NOTE: costs are approximate for a 20-mouse study

Service PCCR Rate
Consultation No Cost
Grant Writing No Cost
HFA  $  1,600
LD50  $  1,100
MTD  $  1,100
Tissue Collection for PK  $  1,400
Efficacy Study  $  2,000
Animal Protocol Preparation No Cost

 

Contact Information & Location

  • Purdue University Center for Cancer Research
    Hansen Life Sciences Research Building
    201 S. University Street
    West Lafayette, IN 47907-2064

  • Phone: (765) 494-9129
    Fax: (765) 494-9193
    Contact us with questions at:
    cancerresearch@purdue.edu

© Copyright 2014 The Purdue University Center for Cancer Research is the first NCI funded Center in Indiana.